SAR405 R enantiomer ( —— )

Catalog No. M23883 CAS No. 1946010-79-2

SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is an inhibitor of PIK3C3/Vps34.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

SAR405 R enantiomer
Note

Research use only, not for human use.
Brief Description

SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is an inhibitor of PIK3C3/Vps34.
Description

SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is an inhibitor of PIK3C3/Vps34.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PIK3C3/Vps34.
Research Area

——
Indication

——

Chemical Information

CAS Number

1946010-79-2
Formula Weight

443.9
Molecular Formula

C19H21ClF3N5O2
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL (225.30 mM; Need ultrasonic)
SMILES

O=C1C=C(N2[C@H](C)COCC2)N=C3N1CC[C@H](C(F)(F)F)N3CC4=CC(Cl)=CN=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Pasquier B. SAR405, a PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells. Autophagy. 2015 Apr 3;11(4):725-6.

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